Endocrine Abstracts

Introduction: Diabetic autonomic neuropathy (DAN) and CAN as one of its most common manifestations are serious complication of type 1 and type 2 diabetes mellitus leading to a significant increase in morbidity and mortality. Case presentationA 51-year old male, diagnosed with T2DM for 25 years, complicated by stage III diabetic polyneuropathy, proliferative retinopathy and several amputations on both feet, treated with Metformin (2g/day), Glargine (26 IU/day) and Aspart (21 IU...

Objectives: To assess the prevalence of diabetic peripheral neuropathy (DPN) among futsal players participating in the 2017 edition of the European Futsal Championship for people with diabetes (DiaEuro).Methods: In this cross-sectional study were included 94 amateur/professional futsal player, from 9 European countries. The evaluation was made based on the data extracted from the standard medical certificate completed by each player’s diabetologist....

Polyglandular autoimmune syndromes (PAS) are a heterogeneous group of rare diseases characterized by autoimmune activity against more than one endocrine organ, although non-endocrine organs can be affected. PAS type IV is a rare syndrome characterized by the association of autoimmune endocrine gland disorder which doesn’t fulfill the criteria of PAS type I-III. A 35-years old female diagnosed with alopecia areata and latent autoimmune diabetes of the adult (LADA) one year...

Background: Resistance to thyroid hormone beta (RTHβ) is an inherited syndrome of reduced tissue responsiveness to thyroid hormones (THs). It is driven in 85% of cases by mutations in the thyroid hormone receptor beta (THRb). The estimated incidence is 1:40.000 to 1:19.000 live births. We report the clinical, laboratory, and genetic analysis of a patient with this disorder.Case report: A 12-year-old boy with a history of Attention-Deficit/H...

Intentional insulin overdose in diabetic patients is a rare critical situation. The severity is due to numerous neurological complications, electrolyte disturbances, liver and lung damage or death.Case report: A 65-year-old male, with significant cardiac and pulmonary pathology, diagnosed with type 2 diabetes since 1996 and treated with glargine (70 U/day) and aspart (68 U/day) insulin is admitted to our centre via ER (emergency room) after an episode of...

Intentional insulin overdose in diabetic patients is a rare critical situation. The severity is due to numerous neurological complications, electrolyte disturbances, liver and lung damage or death.A 76-years old female, with significant cardiac pathology, diagnosed with type 2 diabetes and treated with Humalog Mix50® 0-0-24 U/day, is admitted to our center via ER (emergency room) after an episode of severe hypoglycemia after administratio...

Introduction: Type 1 diabetes mellitus (T1DM) is the most common form of diabetes in children and young adults. Though T1DM often presents in an acute manner, it may be preceded by a prodromal period, often extending over years.Case report: A 19-year-old male, diagnosed with T1DM at the age of 15, with no insulin treatment, was admitted to our department for high glycemic value (G) of 365 mg/dl on a routine exam at his GP. At diagnosis the patient was as...

In type 1 diabetes athletes, the proper adjustments of insulin doses and carbs intake are essential in order to avoid a hypoglycemic event that could affect the sport performances.The aim of the study was to assess the risk of hypoglycemia, the insulin and glycemic variability in 2 different days (with and without physical activity) in a group of nine players with type 1 diabetes, members of the Romania diabetes futsal team (twice European champion)....

Introduction and purpose: Acromegaly is characterised by a chronic increase of GH and IGF-1 levels that may induce various clinical symptoms and multisystem comorbidities. The purpose of this study is to evaluate the type and frequency of thyroid disease most often associated with acromegaly patients.Material and methods: We conducted a retrospective observational study analysing the data from the observation charts of 77 patients with acromegaly (58 fem...

Nesidioblastosis is defined as a diffuse proliferation of primitive pancreatic islet cells budding from ductal epithelium. This condition can cause hypoglycaemia in infants as a result of mutations in the sulfonylurea receptor or in the anatomically linked potassium channel. In adults, this disease occurs independently from these genetic mutations.Case report: A 41-year-old male was referred to our center via emergency room with suspicion of an insulinom...